An open runtime & marketplace for genomics

Read your own DNA, on your own computer.

CommonSense reads the DNA file you already have — from 23andMe, Ancestry, MyHeritage, or a VCF — and runs a growing library of analyses on it, entirely on your own computer. No account, no upload. Your DNA never leaves your device.

How it works

An app on the surface. A platform underneath.

01 · Your data

Drop your DNA file

23andMe, Ancestry, MyHeritage exports — plus VCF, FASTA, and BAM. Parsed in a few seconds and sealed in an encrypted local vault, unlocked by your password and a recovery phrase you keep on paper. No account. No upload.

02 · The analysis

Runs privately on your Mac

Every analysis runs in a locked-down space on your own computer — no internet access, no reach into your other files. Your data goes in; only the result comes out. Nothing is sent anywhere.

03 · The library

Install from an open library

A growing library of analyses you install on demand — traits like lactase persistence and alcohol flush today, with more added all the time. Authored by us now, and by a wider community of contributors next.

Built for the agent era

New analyses, written by anyone — even an AI.

Other DNA apps give you a fixed set of reports one company decided to build. CommonSense is open: describe a new analysis in plain language and an AI writes it for you — grounded in real published research and added to your library. People and AI agents extend the library through the same open standard, so what your DNA can tell you keeps growing, with no gatekeeper. And because the AI only ever sees the request and the code it writes — never your DNA — the analysis it builds still runs entirely on your own computer.

Privacy architecture Your DNA file, stored encrypted, and the analysis that runs on it all stay on your own computer. Only your request and the code the AI writes cross to the AI model — never your DNA. YOUR COMPUTER Your DNA file Stored encrypted on your device Analysis runs here — offline Your DNA never leaves this box. THE AI The AI you choose Claude · ChatGPT · Grok · or local Cloud, or fully offline. task · schema · code · errors the algorithm it writes
The AI never sees your DNA. Only your request and the code it writes cross the line — your DNA file and every result stay on your computer.

Your data stays on your device. The analyses you run are sealed off from the internet and from your files — built into the architecture, not just a privacy policy.

Private by design

What stays on your device

Everything. Your DNA and every result.

Your DNA file and every result stay on your computer — encrypted, and openable only with your password and a recovery phrase you keep. Nothing is ever uploaded, and there's no account.

What you can trust

Every analysis is checked before it runs.

Each analysis is reviewed and cryptographically signed before it reaches you, and the app re-checks that signature on your device before running it. A tampered or unverified analysis simply won't run.

The other side of the marketplace

Publish once. Reach every machine running CommonSense.

The contributor pipeline is a machine-readable standard, end to end. Write your algorithm against a published schema; the dev-kit validates it locally; submit; we review; the marketplace co-signs it and promotes it to the public catalog — the same contract for humans and autonomous agents alike. One runtime to target, every CommonSense user to reach.